Who am I
Hello, I’m Jiazhen Liu, a dedicated researcher with a passion for integrating data science and biomedical engineering to solve complex health challenges. My expertise lies in developing advanced statistical models and predictive algorithms that drive impactful discoveries in medical research.
My journey began with a fascination for biomedical systems, and over time, I honed my skills through rigorous academic training and hands-on research. From optimizing machine learning models for cancer risk assessment to designing robust workflows for RNA sequencing data analysis, I have built a foundation in both theoretical knowledge and practical applications. Today, I apply my skills to tackle challenges in public health and biotechnology, driven by a desire to contribute to the advancement of healthcare technologies.
What I Do
I specialize in developing precise molecular biology techniques that drive innovation in biomedical research and early disease detection. My expertise includes:
Genetic Engineering & Circuit Design
Developing and validating gene constructs using molecular techniques like plasmid ligation, Gibson assembly, and restriction digestion for applications in early cancer detection and synthetic biology.
RNA and DNA Manipulation
Performing RNA purification, cDNA synthesis, and PCR to support genetic studies, ensuring high fidelity in gene expression and sequencing.
Protein Analysis and Assays
Utilizing assays such as ELISA and qPCR to measure protein levels and gene expression, providing insights into cellular mechanisms and therapeutic targets.
Data-Driven Insights for Molecular Research
Integrating statistical data analysis and machine learning to enhance the accuracy and efficiency of biological experiments, driving data-informed decisions in research.
To find more about my experiences
Work & Project Experiences
2023/02 – 2024/05
Prediction Models on COVID-19 & Lung Cancer
Columbia University Irving Medical Center
I built predictive models for lung cancer risk and COVID-19 severity, using Lasso regression, Random Forest, and Gradient Boosting Machines. I conducted data preprocessing and hyperparameter tuning, achieving high accuracy and identifying key predictors.
2023/05 – 2023/09
Bioinformatics Associate
National Laboratory of Protein and Peptide Drugs, Chinese Academy of Science
As a Biostatistics Associate, I developed an RNA-seq workflow to investigate potassium ion imbalances in tumors, performing quality control, sequence alignment, and differential gene analysis. I visualized results with heat maps and volcano plots and created a user-friendly interface to streamline analysis.
2020/02 – 2022/05
Research Assistant
Wilson Wong Lab, Boston University
As a Research Assistant, I led a project focused on genetic circuits for early cancer detection. I performed molecular cloning techniques such as plasmid ligation and Gibson assembly, contributing to innovative advancements in synthetic biology.
2022/02 – 2022/05
Teaching Assistant
Boston University, BE755: Molecular System and Synthetic Biology Lab
As a Teaching Assistant, I instructed students on techniques like transfection and qPCR, developed lab protocols, and monitored experiments. I ensured accurate results and enhanced students’ understanding of synthetic biology applications.